SHORT ANSWER:
I don't vaccinate beyond 1 year and only once more for rabies (once every 3 years). Truth be told - I avoid Rabies when the dog hits 6 or 7 years - and won't do it. Its simply not worth it to me.
My personal view on vaccination is to emulate Jean Dodd's minimal vaccine protocol which is for me a happy medium. And then dependant on where you live, and what regional risks are present, I would consider non-core vaccines. You can titre after vaccination to verify immune response.
Attached is her link - many exist - google Jean Dodds.
http://drjeandoddspethealthresource.tumblr.com/post/34024828409/dodds-canine-vaccination-protocol-2012
LONG ANSWER: The problem with science and claims of "peer review" fall short when we 27,000 human deaths attributed to the heart drug Vioxx
http://www.nbcnews.com/id/6192603/print/1/displaymode/1098/
Interesting to note, this same drug was APPROVED by the FDA in Clinical trials in spite of the fact that during trials it killed people too.
Perhaps the only thing proved by the little experiment is that if it kills you in a trial - it will continue to do so once marketed to the uninformed public.
Another recent example of science and the process of "proving" safety is neonicotinoids used in crops such as corn and soy which are now highly suspect in the overwhelming declines of honey bees around the world.
Sadly Canada is falling behind the European union who has put a moratorium on the product (used in Genetically modified organism crops) but mounting pressure combined with the real threat that a loss of bee population will have on all living things is hopefully going to yield changes here.
http://www.cbc.ca/news/canada/story/2013/07/03/f-dead-bees.html
These SAME products were approved once again by (you guessed it) the FDA through a peer reviewed double blind study.
The list is endless - dog food is another - the preservatives ethoxiquin (spelling) formulated as a tire stabilizer and used widely in pet foods in the 1990's distributed by Monsanto ...and again approved by the FDA (which there is strong evidence the entire process was corrupted by FDA hiring previous Monsanto employees who then became the peer reviewer for the drug approval) - anyway, its actually sickening and if you want to learn more, google You Tube "The world according to Monsanto".
SO - the argument that people who believe life is better living through science and homeopathy is 'quackery" is shallow and weak. Its a refusal to be open minded and personally, I think it must be easy - because by following what is "prescribed" without ever questioning authority - it deflects risk and responsibility to someone else. If the dog died- its NOT your fault because you VACCINATED.
End of.
Flip side to that is: We cannot paint ALL science with the same brush. We cannot dismiss the real advances medicine has made and the quality of life improvements we take for granted now - all do to the scientific process. Science is a good thing - and I agree that having witnessed the parvo epidemic of the 1980's that wiped out many Doberman kennels - its not something we should dismiss.
Tthe challenge is discerning what is good from what is bad and making informed choices.
In terms of nosodes in lieu of vaccination, well, I'm a lay homeopath and I have not used them. Why? Because they are too obscure for even my pallet and I simply cannot find sufficient proof in a wide enough sample of patients (vets) that will convince me to switch. That doesn't mean they don't work - because (again) nosodes are not new - flea medication (herbicides) uses nosodes - heart worm medication uses nosodes.
Like anything, the devil is in the details so the rendering process between a flea spray used to kill fleas on your dog and a homeopathic nosode is different. Its kind of like saying aspirin is natural because it comes from a plant. We use the words "natural" and "holistic" in very broad brush terms which are deceiving.
On a personal note, I HAVE taken homeopathic nosodes for my own health ( a nosode exists for small pox which homeopathically I used when I developed shingles) - with some success. (I still went to my Doctor and got drugs) - but even in my own case, where I have a few hundred homoepathics stored in a cupboard - when I know an alternative is available from my Doctor which is proven to work scientifically - without consequences - I take it. Why not?
Its hard to live in absolutes. When I'm dealing with life and death - I tend to avoid extremes unless I have no choice.
My dogs have clearly benefitted from homeopathics in SOME instances and unlike humans dogs don't have the "placebo effect" to factor in.
Yes, I KNOW they work.